CLAIM: The greatest famine in history (Ezek. 9; Dan. 12:1; Mt. 24:21) is depicted as occurring at the end of the age. This prophecy was partially fulfilled in 586 BC. This important verse makes the entire chapter applicable to the final destruction of Jerusalem at the end of the age.
False.
The reference here is most likely due to the verse 9, rendered “Because of all your detestable idols, I will do to you what I have never done before and will never do again.” In this, they would be envisioning the Great Tribulation, which is past in 70AD. A study of Matthew 24 draws out the fact clearly that 70AD was the Great Tribulation (see article here).